Complete metabolic response of metastatic castration‐resistant neuroendocrine carcinoma of the prostate after treatment with RRx‐001 and reintroduced platinum doublets

Presented herein is the case of a heavily pretreated patient with high‐grade neuroendocrine prostate cancer that achieved a complete metabolic response on platinum‐based chemotherapy after treatment with the dual CD‐47 and SIRP‐α inhibitor, RRx‐001, in a Phase II clinical trial.

Detalles Bibliográficos
Autores principales: Ojemuyiwa, Michelle, Zeman, Karen, Spira, Alexander, Oronsky, Bryan, Ray, Carolyn, Trepel, Jane B., Lee, Min‐Jung, Onyiuke, Ifeyinwa, Brzezniak, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293266/
https://www.ncbi.nlm.nih.gov/pubmed/30564353
http://dx.doi.org/10.1002/ccr3.1880
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author Ojemuyiwa, Michelle
Zeman, Karen
Spira, Alexander
Oronsky, Bryan
Ray, Carolyn
Trepel, Jane B.
Lee, Min‐Jung
Onyiuke, Ifeyinwa
Brzezniak, Christina
author_facet Ojemuyiwa, Michelle
Zeman, Karen
Spira, Alexander
Oronsky, Bryan
Ray, Carolyn
Trepel, Jane B.
Lee, Min‐Jung
Onyiuke, Ifeyinwa
Brzezniak, Christina
author_sort Ojemuyiwa, Michelle
collection PubMed
description Presented herein is the case of a heavily pretreated patient with high‐grade neuroendocrine prostate cancer that achieved a complete metabolic response on platinum‐based chemotherapy after treatment with the dual CD‐47 and SIRP‐α inhibitor, RRx‐001, in a Phase II clinical trial.
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spelling pubmed-62932662018-12-18 Complete metabolic response of metastatic castration‐resistant neuroendocrine carcinoma of the prostate after treatment with RRx‐001 and reintroduced platinum doublets Ojemuyiwa, Michelle Zeman, Karen Spira, Alexander Oronsky, Bryan Ray, Carolyn Trepel, Jane B. Lee, Min‐Jung Onyiuke, Ifeyinwa Brzezniak, Christina Clin Case Rep Case Reports Presented herein is the case of a heavily pretreated patient with high‐grade neuroendocrine prostate cancer that achieved a complete metabolic response on platinum‐based chemotherapy after treatment with the dual CD‐47 and SIRP‐α inhibitor, RRx‐001, in a Phase II clinical trial. John Wiley and Sons Inc. 2018-11-05 /pmc/articles/PMC6293266/ /pubmed/30564353 http://dx.doi.org/10.1002/ccr3.1880 Text en © 2018 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Ojemuyiwa, Michelle
Zeman, Karen
Spira, Alexander
Oronsky, Bryan
Ray, Carolyn
Trepel, Jane B.
Lee, Min‐Jung
Onyiuke, Ifeyinwa
Brzezniak, Christina
Complete metabolic response of metastatic castration‐resistant neuroendocrine carcinoma of the prostate after treatment with RRx‐001 and reintroduced platinum doublets
title Complete metabolic response of metastatic castration‐resistant neuroendocrine carcinoma of the prostate after treatment with RRx‐001 and reintroduced platinum doublets
title_full Complete metabolic response of metastatic castration‐resistant neuroendocrine carcinoma of the prostate after treatment with RRx‐001 and reintroduced platinum doublets
title_fullStr Complete metabolic response of metastatic castration‐resistant neuroendocrine carcinoma of the prostate after treatment with RRx‐001 and reintroduced platinum doublets
title_full_unstemmed Complete metabolic response of metastatic castration‐resistant neuroendocrine carcinoma of the prostate after treatment with RRx‐001 and reintroduced platinum doublets
title_short Complete metabolic response of metastatic castration‐resistant neuroendocrine carcinoma of the prostate after treatment with RRx‐001 and reintroduced platinum doublets
title_sort complete metabolic response of metastatic castration‐resistant neuroendocrine carcinoma of the prostate after treatment with rrx‐001 and reintroduced platinum doublets
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293266/
https://www.ncbi.nlm.nih.gov/pubmed/30564353
http://dx.doi.org/10.1002/ccr3.1880
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