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Improving the microbiological diagnosis of tuberculous meningitis: A prospective, international, multicentre comparison of conventional and modified Ziehl–Neelsen stain, GeneXpert, and culture of cerebrospinal fluid

OBJECTIVES: Tuberculous meningitis (TBM) is the severest form of tuberculosis, but current diagnostic tests are insensitive. Recent reports suggest simple modifications to conventional cerebrospinal fluid (CSF) Ziehl–Neelsen (ZN) staining may greatly improve sensitivity. We sought to define the perf...

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Detalles Bibliográficos
Autores principales:	Heemskerk, A. Dorothee, Donovan, Joseph, Thu, Do Dang Anh, Marais, Suzaan, Chaidir, Lidya, Dung, Vu Thi Mong, Centner, Chad M., Ha, Vu Thi Ngoc, Annisa, Jessi, Dian, Sofiati, Bovijn, Louise, Mai, Nguyen Thi Hoang, Phu, Nguyen Hoan, Chau, Nguyen Van Vinh, Ganiem, Ahmad Rizal, Van, Cao Thao, Geskus, Ronald B., Thuong, Nguyen Thuy Thuong, Ruslami, Rovina, Meintjes, Graeme, van Crevel, Reinout, Wilkinson, Robert J., Thwaites, Guy E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	W.B. Saunders 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293313/ https://www.ncbi.nlm.nih.gov/pubmed/30217659 http://dx.doi.org/10.1016/j.jinf.2018.09.003

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