Epidermal growth factor can signal via β-catenin to control proliferation of mesenchymal stem cells independently of canonical Wnt signalling

Bone marrow mesenchymal stem/stromal cells (MSCs) maintain bone homeostasis and repair through the ability to expand in response to mitotic stimuli and differentiate into skeletal lineages. Signalling mechanisms that enable precise control of MSC function remain unclear. Here we report that by initi...

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Detalles Bibliográficos
Autores principales: Knight, Charlotte, James, Sally, Kuntin, David, Fox, James, Newling, Katherine, Hollings, Sam, Pennock, Rebecca, Genever, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293317/
https://www.ncbi.nlm.nih.gov/pubmed/30287279
http://dx.doi.org/10.1016/j.cellsig.2018.09.021

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