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Attenuation of PKCδ enhances metabolic activity and promotes expansion of blood progenitors
A finely tuned balance of self‐renewal, differentiation, proliferation, and survival governs the pool size and regenerative capacity of blood‐forming hematopoietic stem and progenitor cells (HSPCs). Here, we report that protein kinase C delta (PKCδ) is a critical regulator of adult HSPC number and f...
Autores principales: | Rao, Tata Nageswara, Gupta, Manoj K, Softic, Samir, Wang, Leo D, Jang, Young C, Thomou, Thomas, Bezy, Olivier, Kulkarni, Rohit N, Kahn, C Ronald, Wagers, Amy J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293338/ https://www.ncbi.nlm.nih.gov/pubmed/30446598 http://dx.doi.org/10.15252/embj.2018100409 |
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