Cargando…
The status and health burden of neurocysticercosis in Mbulu district, northern Tanzania
OBJECTIVE: The objective of this study was to assess the extent and health burden of neurocysticercosis in the general community of the Mbulu district, northern Tanzania. About 1051 randomly select participants were screened for human cysticercosis. The Cysticercus Western Blot IgG and Computed Tomo...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293552/ https://www.ncbi.nlm.nih.gov/pubmed/30545404 http://dx.doi.org/10.1186/s13104-018-3999-9 |
_version_ | 1783380558459437056 |
---|---|
author | Mwang’onde, Beda John Chacha, Mwita John Nkwengulila, Gamba |
author_facet | Mwang’onde, Beda John Chacha, Mwita John Nkwengulila, Gamba |
author_sort | Mwang’onde, Beda John |
collection | PubMed |
description | OBJECTIVE: The objective of this study was to assess the extent and health burden of neurocysticercosis in the general community of the Mbulu district, northern Tanzania. About 1051 randomly select participants were screened for human cysticercosis. The Cysticercus Western Blot IgG and Computed Tomography scan were used to detect infection by cysticerci. The DALYs was used to assess the community’s health burden vis-a-vis neurocysticercosis. RESULTS: The sero-prevalence of HCC was 16.27%. About 76% of 25 selected human cysticercosis sero-positives had neurocysticercosis suggestive lesions on CT scan and 74% had history of epilepsy. Epilepsy caused 2.8 years of life lost and 2.2 healthy years of life lost due to disability per 1000 person-years in Mbulu. The average DALYs imposed due to neurocysticercosis and epilepsy were 3.0 and 3.9 per 1000 person-years, respectively. Neurocysticercosis is a serious public health concern in northern Tanzania. |
format | Online Article Text |
id | pubmed-6293552 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-62935522018-12-18 The status and health burden of neurocysticercosis in Mbulu district, northern Tanzania Mwang’onde, Beda John Chacha, Mwita John Nkwengulila, Gamba BMC Res Notes Research Note OBJECTIVE: The objective of this study was to assess the extent and health burden of neurocysticercosis in the general community of the Mbulu district, northern Tanzania. About 1051 randomly select participants were screened for human cysticercosis. The Cysticercus Western Blot IgG and Computed Tomography scan were used to detect infection by cysticerci. The DALYs was used to assess the community’s health burden vis-a-vis neurocysticercosis. RESULTS: The sero-prevalence of HCC was 16.27%. About 76% of 25 selected human cysticercosis sero-positives had neurocysticercosis suggestive lesions on CT scan and 74% had history of epilepsy. Epilepsy caused 2.8 years of life lost and 2.2 healthy years of life lost due to disability per 1000 person-years in Mbulu. The average DALYs imposed due to neurocysticercosis and epilepsy were 3.0 and 3.9 per 1000 person-years, respectively. Neurocysticercosis is a serious public health concern in northern Tanzania. BioMed Central 2018-12-13 /pmc/articles/PMC6293552/ /pubmed/30545404 http://dx.doi.org/10.1186/s13104-018-3999-9 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Note Mwang’onde, Beda John Chacha, Mwita John Nkwengulila, Gamba The status and health burden of neurocysticercosis in Mbulu district, northern Tanzania |
title | The status and health burden of neurocysticercosis in Mbulu district, northern Tanzania |
title_full | The status and health burden of neurocysticercosis in Mbulu district, northern Tanzania |
title_fullStr | The status and health burden of neurocysticercosis in Mbulu district, northern Tanzania |
title_full_unstemmed | The status and health burden of neurocysticercosis in Mbulu district, northern Tanzania |
title_short | The status and health burden of neurocysticercosis in Mbulu district, northern Tanzania |
title_sort | status and health burden of neurocysticercosis in mbulu district, northern tanzania |
topic | Research Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293552/ https://www.ncbi.nlm.nih.gov/pubmed/30545404 http://dx.doi.org/10.1186/s13104-018-3999-9 |
work_keys_str_mv | AT mwangondebedajohn thestatusandhealthburdenofneurocysticercosisinmbuludistrictnortherntanzania AT chachamwitajohn thestatusandhealthburdenofneurocysticercosisinmbuludistrictnortherntanzania AT nkwengulilagamba thestatusandhealthburdenofneurocysticercosisinmbuludistrictnortherntanzania AT mwangondebedajohn statusandhealthburdenofneurocysticercosisinmbuludistrictnortherntanzania AT chachamwitajohn statusandhealthburdenofneurocysticercosisinmbuludistrictnortherntanzania AT nkwengulilagamba statusandhealthburdenofneurocysticercosisinmbuludistrictnortherntanzania |