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The status and health burden of neurocysticercosis in Mbulu district, northern Tanzania

OBJECTIVE: The objective of this study was to assess the extent and health burden of neurocysticercosis in the general community of the Mbulu district, northern Tanzania. About 1051 randomly select participants were screened for human cysticercosis. The Cysticercus Western Blot IgG and Computed Tomo...

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Autores principales: Mwang’onde, Beda John, Chacha, Mwita John, Nkwengulila, Gamba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293552/
https://www.ncbi.nlm.nih.gov/pubmed/30545404
http://dx.doi.org/10.1186/s13104-018-3999-9
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author Mwang’onde, Beda John
Chacha, Mwita John
Nkwengulila, Gamba
author_facet Mwang’onde, Beda John
Chacha, Mwita John
Nkwengulila, Gamba
author_sort Mwang’onde, Beda John
collection PubMed
description OBJECTIVE: The objective of this study was to assess the extent and health burden of neurocysticercosis in the general community of the Mbulu district, northern Tanzania. About 1051 randomly select participants were screened for human cysticercosis. The Cysticercus Western Blot IgG and Computed Tomography scan were used to detect infection by cysticerci. The DALYs was used to assess the community’s health burden vis-a-vis neurocysticercosis. RESULTS: The sero-prevalence of HCC was 16.27%. About 76% of 25 selected human cysticercosis sero-positives had neurocysticercosis suggestive lesions on CT scan and 74% had history of epilepsy. Epilepsy caused 2.8 years of life lost and 2.2 healthy years of life lost due to disability per 1000 person-years in Mbulu. The average DALYs imposed due to neurocysticercosis and epilepsy were 3.0 and 3.9 per 1000 person-years, respectively. Neurocysticercosis is a serious public health concern in northern Tanzania.
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spelling pubmed-62935522018-12-18 The status and health burden of neurocysticercosis in Mbulu district, northern Tanzania Mwang’onde, Beda John Chacha, Mwita John Nkwengulila, Gamba BMC Res Notes Research Note OBJECTIVE: The objective of this study was to assess the extent and health burden of neurocysticercosis in the general community of the Mbulu district, northern Tanzania. About 1051 randomly select participants were screened for human cysticercosis. The Cysticercus Western Blot IgG and Computed Tomography scan were used to detect infection by cysticerci. The DALYs was used to assess the community’s health burden vis-a-vis neurocysticercosis. RESULTS: The sero-prevalence of HCC was 16.27%. About 76% of 25 selected human cysticercosis sero-positives had neurocysticercosis suggestive lesions on CT scan and 74% had history of epilepsy. Epilepsy caused 2.8 years of life lost and 2.2 healthy years of life lost due to disability per 1000 person-years in Mbulu. The average DALYs imposed due to neurocysticercosis and epilepsy were 3.0 and 3.9 per 1000 person-years, respectively. Neurocysticercosis is a serious public health concern in northern Tanzania. BioMed Central 2018-12-13 /pmc/articles/PMC6293552/ /pubmed/30545404 http://dx.doi.org/10.1186/s13104-018-3999-9 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
Mwang’onde, Beda John
Chacha, Mwita John
Nkwengulila, Gamba
The status and health burden of neurocysticercosis in Mbulu district, northern Tanzania
title The status and health burden of neurocysticercosis in Mbulu district, northern Tanzania
title_full The status and health burden of neurocysticercosis in Mbulu district, northern Tanzania
title_fullStr The status and health burden of neurocysticercosis in Mbulu district, northern Tanzania
title_full_unstemmed The status and health burden of neurocysticercosis in Mbulu district, northern Tanzania
title_short The status and health burden of neurocysticercosis in Mbulu district, northern Tanzania
title_sort status and health burden of neurocysticercosis in mbulu district, northern tanzania
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293552/
https://www.ncbi.nlm.nih.gov/pubmed/30545404
http://dx.doi.org/10.1186/s13104-018-3999-9
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