USF1 deficiency alleviates inflammation, enhances cholesterol efflux and prevents cholesterol accumulation in macrophages

BACKGROUND: The focus of studies on high-density lipoproteins (HDL) has shifted from HDL-cholesterol (HDL-C) to HDL function. We recently demonstrated that low USF1 expression in mice and humans associates with high plasma HDL-C and low triglyceride levels, as well as protection against obesity, ins...

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Detalles Bibliográficos
Autores principales: Ruuth, Maija, Soronen, Jarkko, Kaiharju, Essi, Merikanto, Krista, Perttilä, Julia, Metso, Jari, Lee-Rueckert, Miriam, Taskinen, Marja-Riitta, Kovanen, Petri T., Öörni, Katariina, Olkkonen, Vesa M., Jauhiainen, Matti S., Laurila, Pirkka-Pekka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293625/
https://www.ncbi.nlm.nih.gov/pubmed/30545366
http://dx.doi.org/10.1186/s12944-018-0930-2

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