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Production efficiency of the bacterial non-ribosomal peptide indigoidine relies on the respiratory metabolic state in S. cerevisiae

BACKGROUND: Beyond pathway engineering, the metabolic state of the production host is critical in maintaining the efficiency of cellular production. The biotechnologically important yeast Saccharomyces cerevisiae adjusts its energy metabolism based on the availability of oxygen and carbon sources. T...

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Detalles Bibliográficos
Autores principales: Wehrs, Maren, Prahl, Jan-Philip, Moon, Jadie, Li, Yuchen, Tanjore, Deepti, Keasling, Jay D., Pray, Todd, Mukhopadhyay, Aindrila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293659/
https://www.ncbi.nlm.nih.gov/pubmed/30545355
http://dx.doi.org/10.1186/s12934-018-1045-1