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Production efficiency of the bacterial non-ribosomal peptide indigoidine relies on the respiratory metabolic state in S. cerevisiae
BACKGROUND: Beyond pathway engineering, the metabolic state of the production host is critical in maintaining the efficiency of cellular production. The biotechnologically important yeast Saccharomyces cerevisiae adjusts its energy metabolism based on the availability of oxygen and carbon sources. T...
Autores principales: | Wehrs, Maren, Prahl, Jan-Philip, Moon, Jadie, Li, Yuchen, Tanjore, Deepti, Keasling, Jay D., Pray, Todd, Mukhopadhyay, Aindrila |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293659/ https://www.ncbi.nlm.nih.gov/pubmed/30545355 http://dx.doi.org/10.1186/s12934-018-1045-1 |
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