Control of T(reg) cell homeostasis and immune equilibrium by Lkb1 in dendritic cells

To balance immunity and tolerance, the endogenous pool of Foxp3(+) regulatory T (T(reg)) cells is tightly controlled, but the underlying mechanisms of this control remain poorly understood. Here we show that the number of T(reg) cells is negatively regulated by the kinase Lkb1 in dendritic cells (DC...

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Detalles Bibliográficos
Autores principales: Chen, Song, Fang, Lijun, Guo, Wei, Zhou, Yushan, Yu, Gang, Li, Wenwen, Dong, Kui, Liu, Jingru, Luo, Yuechen, Wang, Bing, Li, Zhonglong, Zhao, Chunxiao, Sun, Zhina, Shen, Yue, Leng, Qibing, Zhou, Dongming, Han, Zhongchao, Huang, Huifang, Ren, He, Xu, Guogang, Feng, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294005/
https://www.ncbi.nlm.nih.gov/pubmed/30546010
http://dx.doi.org/10.1038/s41467-018-07545-8

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