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Drug delivery to atherosclerotic plaques using superparamagnetic iron oxide nanoparticles

INTRODUCTION: Magnetic drug targeting utilizes superparamagnetic iron oxide nanoparticles (SPIONs) to accumulate drugs in specified vasculature regions. METHODS: We produced SPIONs conjugated with dexamethasone phosphate (SPION-DEXA). The efficacy of magnetic drug targeting was investigated in a rab...

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Detalles Bibliográficos
Autores principales: Matuszak, Jasmin, Lutz, Barbara, Sekita, Aleksander, Zaloga, Jan, Alexiou, Christoph, Lyer, Stefan, Cicha, Iwona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294059/
https://www.ncbi.nlm.nih.gov/pubmed/30587970
http://dx.doi.org/10.2147/IJN.S179273