Cargando…

Drug delivery to atherosclerotic plaques using superparamagnetic iron oxide nanoparticles

INTRODUCTION: Magnetic drug targeting utilizes superparamagnetic iron oxide nanoparticles (SPIONs) to accumulate drugs in specified vasculature regions. METHODS: We produced SPIONs conjugated with dexamethasone phosphate (SPION-DEXA). The efficacy of magnetic drug targeting was investigated in a rab...

Descripción completa

Detalles Bibliográficos
Autores principales:	Matuszak, Jasmin, Lutz, Barbara, Sekita, Aleksander, Zaloga, Jan, Alexiou, Christoph, Lyer, Stefan, Cicha, Iwona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294059/ https://www.ncbi.nlm.nih.gov/pubmed/30587970 http://dx.doi.org/10.2147/IJN.S179273

Ejemplares similares

Tissue Plasminogen Activator Binding to Superparamagnetic Iron Oxide Nanoparticle—Covalent Versus Adsorptive Approach
por: Friedrich, Ralf P, et al.
Publicado: (2016)

Non-immunogenic dextran-coated superparamagnetic iron oxide nanoparticles: a biocompatible, size-tunable contrast agent for magnetic resonance imaging
por: Unterweger, Harald, et al.
Publicado: (2017)

A novel human artery model to assess the magnetic accumulation of SPIONs under flow conditions
por: Janikowska, Agata, et al.
Publicado: (2017)

Synthesis and Characterization of Tissue Plasminogen Activator—Functionalized Superparamagnetic Iron Oxide Nanoparticles for Targeted Fibrin Clot Dissolution
por: Heid, Susanne, et al.
Publicado: (2017)

Dextran-coated superparamagnetic iron oxide nanoparticles for magnetic resonance imaging: evaluation of size-dependent imaging properties, storage stability and safety
por: Unterweger, Harald, et al.
Publicado: (2018)

Development of a lauric acid/albumin hybrid iron oxide nanoparticle system with improved biocompatibility
por: Zaloga, Jan, et al.
Publicado: (2014)

Functionalized Superparamagnetic Iron Oxide Nanoparticles (SPIONs) as Platform for the Targeted Multimodal Tumor Therapy
por: Janko, Christina, et al.
Publicado: (2019)

Genotoxicity of Superparamagnetic Iron Oxide Nanoparticles in Granulosa Cells
por: Pöttler, Marina, et al.
Publicado: (2015)

Synthesis and Characterization of Citrate-Stabilized Gold-Coated Superparamagnetic Iron Oxide Nanoparticles for Biomedical Applications
por: Stein, René, et al.
Publicado: (2020)

Iron Oxide Nanoparticles in Regenerative Medicine and Tissue Engineering
por: Friedrich, Ralf P., et al.
Publicado: (2021)

Mitoxantrone Loaded Superparamagnetic Nanoparticles for Drug Targeting: A Versatile and Sensitive Method for Quantification of Drug Enrichment in Rabbit Tissues Using HPLC-UV
por: Tietze, Rainer, et al.
Publicado: (2010)

Different Storage Conditions Influence Biocompatibility and Physicochemical Properties of Iron Oxide Nanoparticles
por: Zaloga, Jan, et al.
Publicado: (2015)

Citrate-Coated Superparamagnetic Iron Oxide Nanoparticles Enable a Stable Non-Spilling Loading of T Cells and Their Magnetic Accumulation
por: Boosz, Philipp, et al.
Publicado: (2021)

Magnetic Accumulation of SPIONs under Arterial Flow Conditions: Effect of Serum and Red Blood Cells
por: Hennig, Till L., et al.
Publicado: (2019)

Macrophage uptake switches on OCT contrast of superparamagnetic nanoparticles for imaging of atherosclerotic plaques
por: Ariza de Schellenberger, Angela, et al.
Publicado: (2018)

Development and characterization of magnetic iron oxide nanoparticles with a cisplatin-bearing polymer coating for targeted drug delivery
por: Unterweger, Harald, et al.
Publicado: (2014)

IL-6-targeted ultrasmall superparamagnetic iron oxide nanoparticles for optimized MRI detection of atherosclerotic vulnerable plaques in rabbits
por: Mo, Huaqiang, et al.
Publicado: (2020)

Flow cytometry for intracellular SPION quantification: specificity and sensitivity in comparison with spectroscopic methods
por: Friedrich, Ralf P, et al.
Publicado: (2015)

Impact of Superparamagnetic Iron Oxide Nanoparticles on Vocal Fold Fibroblasts: Cell Behavior and Cellular Iron Kinetics
por: Pöttler, Marina, et al.
Publicado: (2017)

Facile preparation of multifunctional superparamagnetic PHBV microspheres containing SPIONs for biomedical applications
por: Li, Wei, et al.
Publicado: (2016)

Treatment Efficiency of Free and Nanoparticle-Loaded Mitoxantrone for Magnetic Drug Targeting in Multicellular Tumor Spheroids
por: Hornung, Annkathrin, et al.
Publicado: (2015)

Vascular and plaque imaging with ultrasmall superparamagnetic particles of iron oxide
por: Alam, Shirjel R., et al.
Publicado: (2015)

Ultrasonic Imaging of Carotid Inflammatory Plaque with Superparamagnetic Nanoparticles
por: Li, Wei, et al.
Publicado: (2021)

Functionalization Of T Lymphocytes With Citrate-Coated Superparamagnetic Iron Oxide Nanoparticles For Magnetically Controlled Immune Therapy
por: Mühlberger, Marina, et al.
Publicado: (2019)

Magnetite-Arginine Nanoparticles as a Multifunctional Biomedical Tool
por: Reichel, Victoria E., et al.
Publicado: (2020)

Preparation and characterization of superparamagnetic iron oxide nanoparticles for magnetically guided drug delivery
por: Kumar, Pramod, et al.
Publicado: (2018)

Applications of superparamagnetic iron oxide nanoparticles in drug and therapeutic delivery, and biotechnological advancements
por: Suciu, Maria, et al.
Publicado: (2020)

Human T cells loaded with superparamagnetic iron oxide nanoparticles retain antigen-specific TCR functionality
por: Pfister, Felix, et al.
Publicado: (2023)

Tracking stem cells with superparamagnetic iron oxide nanoparticles: perspectives and considerations
por: Jasmin,, et al.
Publicado: (2017)

Retracted: Ultrasonic Imaging of Carotid Inflammatory Plaque with Superparamagnetic Nanoparticles
por: Methods in Medicine, Computational and Mathematical
Publicado: (2023)

Washing effect on superparamagnetic iron oxide nanoparticles
por: Mireles, Laura-Karina, et al.
Publicado: (2016)

Hybrid Radiobioconjugated Superparamagnetic Iron Oxide-Based Nanoparticles for Multimodal Cancer Therapy
por: Żuk, Michał, et al.
Publicado: (2021)

MRI tracing of ultrasmall superparamagnetic iron oxide nanoparticle-labeled endothelial progenitor cells for repairing atherosclerotic vessels in rabbits
por: Wei, Hongxia, et al.
Publicado: (2020)

Superparamagnetic Iron Oxide Nanoparticles Carrying Chemotherapeutics Improve Drug Efficacy in Monolayer and Spheroid Cell Culture by Enabling Active Accumulation
por: Nguyen, Khanh, et al.
Publicado: (2020)

Extracellular Vesicle-Mediated Delivery of Ultrasmall Superparamagnetic Iron Oxide Nanoparticles to Mice Brain
por: Kutchy, Naseer A., et al.
Publicado: (2022)

Selection of potential iron oxide nanoparticles for breast cancer treatment based on in vitro cytotoxicity and cellular uptake
por: Poller, Johanna M, et al.
Publicado: (2017)

Comparative in vitro and in vivo Evaluation of Different Iron Oxide-Based Contrast Agents to Promote Clinical Translation in Compliance with Patient Safety
por: Unterweger, Harald, et al.
Publicado: (2023)

Loading of Primary Human T Lymphocytes with Citrate-Coated Superparamagnetic Iron Oxide Nanoparticles Does Not Impair Their Activation after Polyclonal Stimulation
por: Mühlberger, Marina, et al.
Publicado: (2020)

Potential toxicity of superparamagnetic iron oxide nanoparticles (SPION)
por: Singh, Neenu, et al.
Publicado: (2010)

Comprehensive cytotoxicity studies of superparamagnetic iron oxide nanoparticles
por: Patil, Rakesh M., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_cpg6d5ubva2ovs8mvud2lentej