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Is there a Real Correlation between Red Cell Distribution Width and Peripheral Arterial Disease?

BACKGROUND: Few data is available concerning the association between peripheral arterial disease (PAD) and red cell distribution width (RDW). In this study, we analyzed the relationship between RDW and atherosclerosis of the vessels other than coronary arteries in patients who had undergone digital...

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Autores principales: Duman, Enes, Kulaksızoglu, Sevsen, Çifçi, Egemen, Ozulku, Mehmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294085/
https://www.ncbi.nlm.nih.gov/pubmed/30581327
http://dx.doi.org/10.1515/jomb-2017-0028
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author Duman, Enes
Kulaksızoglu, Sevsen
Çifçi, Egemen
Ozulku, Mehmet
author_facet Duman, Enes
Kulaksızoglu, Sevsen
Çifçi, Egemen
Ozulku, Mehmet
author_sort Duman, Enes
collection PubMed
description BACKGROUND: Few data is available concerning the association between peripheral arterial disease (PAD) and red cell distribution width (RDW). In this study, we analyzed the relationship between RDW and atherosclerosis of the vessels other than coronary arteries in patients who had undergone digital substraction angiography (DSA). METHODS: This study included 730 patients who had undergone DSA. Patients were divided into two groups according to their angiographic images. The association between RDW and atherosclerosis of peripheral arteries was analyzed. The relationship between atherosclerosis and smoking, hypertension (HT), diabetes mellitus (DM), hs-CRP, hemoglobin, white blood cell (WBC), triglyceride, total cholesterol, HDL and LDL cholesterol levels was assessed. RESULTS: Atherosclerosis was observed more common in male and patients with older age, HT, DM and smoking (p<0.001). hs-CRP and WBC levels were both in significantly positive association with atherosclerosis (p<0.05). However, there were no significant differences in the RDW levels, hemoglobin, triglyceride, total cholesterol, LDL and HDL cholesterol levels in the groups (p>0.05). CONCLUSION: Our results seem to demonstrate that older age, male gender, HT, DM and smoking are powerful risk factors for PAD. In contrast to the previous reports, RDW levels are found not to be associated with atherosclerosis of peripheral arteries.
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spelling pubmed-62940852018-12-21 Is there a Real Correlation between Red Cell Distribution Width and Peripheral Arterial Disease? Duman, Enes Kulaksızoglu, Sevsen Çifçi, Egemen Ozulku, Mehmet J Med Biochem Original Paper BACKGROUND: Few data is available concerning the association between peripheral arterial disease (PAD) and red cell distribution width (RDW). In this study, we analyzed the relationship between RDW and atherosclerosis of the vessels other than coronary arteries in patients who had undergone digital substraction angiography (DSA). METHODS: This study included 730 patients who had undergone DSA. Patients were divided into two groups according to their angiographic images. The association between RDW and atherosclerosis of peripheral arteries was analyzed. The relationship between atherosclerosis and smoking, hypertension (HT), diabetes mellitus (DM), hs-CRP, hemoglobin, white blood cell (WBC), triglyceride, total cholesterol, HDL and LDL cholesterol levels was assessed. RESULTS: Atherosclerosis was observed more common in male and patients with older age, HT, DM and smoking (p<0.001). hs-CRP and WBC levels were both in significantly positive association with atherosclerosis (p<0.05). However, there were no significant differences in the RDW levels, hemoglobin, triglyceride, total cholesterol, LDL and HDL cholesterol levels in the groups (p>0.05). CONCLUSION: Our results seem to demonstrate that older age, male gender, HT, DM and smoking are powerful risk factors for PAD. In contrast to the previous reports, RDW levels are found not to be associated with atherosclerosis of peripheral arteries. Sciendo 2017-10-28 /pmc/articles/PMC6294085/ /pubmed/30581327 http://dx.doi.org/10.1515/jomb-2017-0028 Text en © 2017 Enes Duman, Sevsen Kulaksızoglu, Egemen Çifçi, Mehmet Ozulku published by Sciendo http://creativecommons.org/licenses/by-nc-nd/4.0 This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.
spellingShingle Original Paper
Duman, Enes
Kulaksızoglu, Sevsen
Çifçi, Egemen
Ozulku, Mehmet
Is there a Real Correlation between Red Cell Distribution Width and Peripheral Arterial Disease?
title Is there a Real Correlation between Red Cell Distribution Width and Peripheral Arterial Disease?
title_full Is there a Real Correlation between Red Cell Distribution Width and Peripheral Arterial Disease?
title_fullStr Is there a Real Correlation between Red Cell Distribution Width and Peripheral Arterial Disease?
title_full_unstemmed Is there a Real Correlation between Red Cell Distribution Width and Peripheral Arterial Disease?
title_short Is there a Real Correlation between Red Cell Distribution Width and Peripheral Arterial Disease?
title_sort is there a real correlation between red cell distribution width and peripheral arterial disease?
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294085/
https://www.ncbi.nlm.nih.gov/pubmed/30581327
http://dx.doi.org/10.1515/jomb-2017-0028
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