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VHL Dependent Expression of REDD1 and PDK3 Proteins in Clear-cell Renal Cell Carcinoma

BACKGROUND: Sporadic clear-cell renal cell carcinoma (ccRCC) is associated with mutations in the VHL gene, upregulated mammalian target of rapamycin (mTOR) activity and glycolytic metabolism. Here, we analyze the effect of VHL mutational status on the expression level of mTOR, eIF4E-BP1, AMPK, REDD1...

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Detalles Bibliográficos
Autores principales:	Ilic, Bojana B, Antic, Jadranka A, Bankovic, Jovana Z, Milicevic, Ivana T, Rodic, Gordana S, Ilic, Dusan S, Tulic, Cane D, Todorovic, Vera N, Damjanovic, Svetozar S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sciendo 2018
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294108/ https://www.ncbi.nlm.nih.gov/pubmed/30581339 http://dx.doi.org/10.1515/jomb-2017-0030

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