Cargando…

MYC Induces a Hybrid Energetics Program Early in Cell Reprogramming

Cell reprogramming is thought to be associated with a full metabolic switch from an oxidative- to a glycolytic-based metabolism. However, neither the dynamics nor the factors controlling this metabolic switch are fully understood. By using cellular, biochemical, protein array, metabolomic, and respi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Prieto, Javier, Seo, Arnold Y., León, Marian, Santacatterina, Fulvio, Torresano, Laura, Palomino-Schätzlein, Martina, Giménez, Karen, Vallet-Sánchez, Azahara, Ponsoda, Xavier, Pineda-Lucena, Antonio, Cuezva, José M., Lippincott-Schwartz, Jennifer, Torres, Josema
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294174/ https://www.ncbi.nlm.nih.gov/pubmed/30472011 http://dx.doi.org/10.1016/j.stemcr.2018.10.018

Ejemplares similares

c-MYC Triggers Lipid Remodelling During Early Somatic Cell Reprogramming to Pluripotency
por: Prieto, Javier, et al.
Publicado: (2021)

Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming
por: Prieto, Javier, et al.
Publicado: (2016)

Mitochondrial Dynamics: In Cell Reprogramming as It Is in Cancer
por: Prieto, Javier, et al.
Publicado: (2017)

Glutamine/glutamate metabolism rewiring in reprogrammed human hepatocyte-like cells
por: Ballester, Maria, et al.
Publicado: (2019)

Correction: Assessment of gold nanoparticles on human peripheral blood cells by metabolic profiling with (1)H-NMR spectroscopy, a novel translational approach on a patient-specific basis
por: Palomino-Schätzlein, Martina, et al.
Publicado: (2017)

Assessment of gold nanoparticles on human peripheral blood cells by metabolic profiling with (1)H-NMR spectroscopy, a novel translational approach on a patient-specific basis
por: Palomino-Schätzlein, Martina, et al.
Publicado: (2017)

Rapid degeneration of iPSC-derived motor neurons lacking Gdap1 engages a mitochondrial-sustained innate immune response
por: León, Marian, et al.
Publicado: (2023)

MYC sensitises cells to apoptosis by driving energetic demand
por: Edwards-Hicks, Joy, et al.
Publicado: (2022)

Analysis of the metabolic proteome of lung adenocarcinomas by reverse-phase protein arrays (RPPA) emphasizes mitochondria as targets for therapy
por: Torresano, Laura, et al.
Publicado: (2022)

In vivo Reprogramming of Cancer Metabolism by MYC
por: Camarda, Roman, et al.
Publicado: (2017)

Metabolic footprint of aging and obesity in red blood cells
por: Domingo-Ortí, Inés, et al.
Publicado: (2021)

Mild Muscle Mitochondrial Fusion Distress Extends Drosophila Lifespan through an Early and Systemic Metabolome Reorganization
por: Tapia, Andrea, et al.
Publicado: (2021)

Metabolic Alterations in a Drosophila Model of Parkinson’s Disease Based on DJ-1 Deficiency
por: Solana-Manrique, Cristina, et al.
Publicado: (2022)

Quantitative analysis of proteins of metabolism by reverse phase protein microarrays identifies potential biomarkers of rare neuromuscular diseases
por: Santacatterina, Fulvio, et al.
Publicado: (2015)

Metabolic fingerprint of insulin resistance in human polymorphonuclear leucocytes
por: Palomino-Schätzlein, Martina, et al.
Publicado: (2018)

Coordinate β-adrenergic inhibition of mitochondrial activity and angiogenesis arrest tumor growth
por: Nuevo-Tapioles, Cristina, et al.
Publicado: (2020)

Pyruvate kinase M2 and the mitochondrial ATPase Inhibitory Factor 1 provide novel biomarkers of dermatomyositis: a metabolic link to oncogenesis
por: Santacatterina, Fulvio, et al.
Publicado: (2017)

Overexpression of Mitochondrial IF1 Prevents Metastatic Disease of Colorectal Cancer by Enhancing Anoikis and Tumor Infiltration of NK Cells
por: González-Llorente, Lucía, et al.
Publicado: (2019)

Characterization of triple‐negative breast cancer preclinical models provides functional evidence of metastatic progression
por: Arroyo‐Crespo, Juan J., et al.
Publicado: (2019)

Temporal Requirements of cMyc Protein for Reprogramming Mouse Fibroblasts
por: Heffernan, Corey, et al.
Publicado: (2012)

BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells
por: Privat, Maud, et al.
Publicado: (2014)

Development of an optimized method for processing peripheral blood mononuclear cells for (1)H-nuclear magnetic resonance-based metabolomic profiling
por: Gómez-Archila, León Gabriel, et al.
Publicado: (2021)

A Review of the Inhibition of the Mitochondrial ATP Synthase by IF1 in vivo: Reprogramming Energy Metabolism and Inducing Mitohormesis
por: García-Aguilar, Ana, et al.
Publicado: (2018)

IF1 reprograms energy metabolism and signals the oncogenic phenotype in cancer
por: Sánchez-Aragó, María, et al.
Publicado: (2012)

Silencing of hepatic fate-conversion factors induce tumorigenesis in reprogrammed hepatic progenitor-like cells
por: Serrano, Felipe, et al.
Publicado: (2016)

MYC-induced reprogramming of glutamine catabolism supports optimal virus replication
por: Thai, Minh, et al.
Publicado: (2015)

BAK/BAX-Mediated Apoptosis Is a Myc-Induced Roadblock to Reprogramming
por: Kim, Esther J.Y., et al.
Publicado: (2018)

KPNA2 promotes metabolic reprogramming in glioblastomas by regulation of c-myc
por: Li, Jie, et al.
Publicado: (2018)

Plasma metabolomics by nuclear magnetic resonance reveals biomarkers and metabolic pathways associated with the control of HIV-1 infection/progression
por: Gómez-Archila, León Gabriel, et al.
Publicado: (2023)

Metabolic Reprogramming After Left Ventricular Assist Device: Remodeling Without Recovery of Cardiac Energetics
por: Rame, J. Eduardo, et al.
Publicado: (2016)

Beyond the Warburg Effect: N-Myc Contributes to Metabolic Reprogramming in Cancer Cells
por: Yoshida, Go J.
Publicado: (2020)

IF1 ablation prevents ATP synthase oligomerization, enhances mitochondrial ATP turnover and promotes an adenosine-mediated pro-inflammatory phenotype
por: Domínguez-Zorita, Sonia, et al.
Publicado: (2023)

GSK3β Inhibition Prevents Macrophage Reprogramming by High-Dose Methotrexate
por: Ríos, Israel, et al.
Publicado: (2022)

NOX4 functions as a mitochondrial energetic sensor coupling cancer metabolic reprogramming to drug resistance
por: Shanmugasundaram, Karthigayan, et al.
Publicado: (2017)

Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogramming
por: Zwaans, Bernadette M. M., et al.
Publicado: (2014)

Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming
por: Hirsch, Calley L., et al.
Publicado: (2015)

Systems level profiling of arginine starvation reveals MYC and ERK adaptive metabolic reprogramming
por: Brashears, Caitlyn B., et al.
Publicado: (2020)

MUC16-mediated activation of mTOR and c-MYC reprograms pancreatic cancer metabolism
por: Shukla, Surendra K., et al.
Publicado: (2015)

The Multifaceted Roles of MYC2 in Plants: Toward Transcriptional Reprogramming and Stress Tolerance by Jasmonate Signaling
por: Song, Cheng, et al.
Publicado: (2022)

TGFβ limits Myc-dependent TCR-induced metabolic reprogramming in CD8(+) T cells
por: Hope, Helen Carrasco, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6hek2cdnoh14foovrvctc892j2