Transcriptome 3′end organization by PCF11 links alternative polyadenylation to formation and neuronal differentiation of neuroblastoma

Diversification at the transcriptome 3′end is an important and evolutionarily conserved layer of gene regulation associated with differentiation and dedifferentiation processes. Here, we identify extensive transcriptome 3′end-alterations in neuroblastoma, a tumour entity with a paucity of recurrent...

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Detalles Bibliográficos
Autores principales: Ogorodnikov, Anton, Levin, Michal, Tattikota, Surendra, Tokalov, Sergey, Hoque, Mainul, Scherzinger, Denise, Marini, Federico, Poetsch, Ansgar, Binder, Harald, Macher-Göppinger, Stephan, Probst, Hans Christian, Tian, Bin, Schaefer, Michael, Lackner, Karl J., Westermann, Frank, Danckwardt, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294251/
https://www.ncbi.nlm.nih.gov/pubmed/30552333
http://dx.doi.org/10.1038/s41467-018-07580-5

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