Cargando…
Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas
Understanding metabolic dysregulation in different disease settings is vital for the safe and effective incorporation of metabolism-targeted therapeutics in the clinic. Here, using transcriptomic data for 10,704 tumor and normal samples from The Cancer Genome Atlas, across 26 disease sites, we prese...
Autores principales: | Rosario, S. R., Long, M. D., Affronti, H. C., Rowsam, A. M., Eng, K. H., Smiraglia, D. J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294258/ https://www.ncbi.nlm.nih.gov/pubmed/30552315 http://dx.doi.org/10.1038/s41467-018-07232-8 |
Ejemplares similares
-
JAZF1: A Metabolic Regulator of Sensitivity to a Polyamine-Targeted Therapy
por: Rosario, Spencer R., et al.
Publicado: (2023) -
Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer
por: Long, Mark D., et al.
Publicado: (2021) -
Pan-cancer molecular analysis of the RB tumor suppressor pathway
por: Knudsen, Erik S., et al.
Publicado: (2020) -
Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy
por: Affronti, Hayley C., et al.
Publicado: (2020) -
Dynamic patterns of DNA methylation in the normal prostate epithelial differentiation program are targets of aberrant methylation in prostate cancer
por: Long, Mark D., et al.
Publicado: (2021)