Increased Calcium Influx through L-type Calcium Channels in Human and Mouse Neural Progenitors Lacking Fragile X Mental Retardation Protein

The absence of FMR1 protein (FMRP) causes fragile X syndrome (FXS) and disturbed FMRP function is implicated in several forms of human psychopathology. We show that intracellular calcium responses to depolarization are augmented in neural progenitors derived from human induced pluripotent stem cells...

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Detalles Bibliográficos
Autores principales: Danesi, Claudia, Achuta, Venkat Swaroop, Corcoran, Padraic, Peteri, Ulla-Kaisa, Turconi, Giorgio, Matsui, Nobuaki, Albayrak, Ilyas, Rezov, Veronika, Isaksson, Anders, Castrén, Maija L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294261/
https://www.ncbi.nlm.nih.gov/pubmed/30503263
http://dx.doi.org/10.1016/j.stemcr.2018.11.003

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