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Adolescent pruning and stabilization of dendritic spines on cortical layer 5 pyramidal neurons do not depend on gonadal hormones

Pyramidal neurons in the neocortex receive a majority of their synapses on dendritic spines, whose growth, gain, and loss regulate the strength and identity of neural connections. Juvenile brains typically show higher spine density and turnover compared to adult brains, potentially enabling greater...

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Detalles Bibliográficos
Autores principales: Boivin, Josiah R., Piekarski, David J., Thomas, A. Wren, Wilbrecht, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294327/
https://www.ncbi.nlm.nih.gov/pubmed/29413532
http://dx.doi.org/10.1016/j.dcn.2018.01.007