Mechanisms of acquired resistance to afatinib clarified with liquid biopsy

Although mechanisms of acquired resistance to 1(st) and 3(rd) generation EGFR-TKI continue to be elucidated, there have been few clinical investigations into the mechanisms of acquired resistance to the 2(nd) generation EGFR-TKI afatinib. We analyzed data from 20 patients with advanced lung adenocar...

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Detalles Bibliográficos
Autores principales: Nakamura, Tomomi, Nakashima, Chiho, Komiya, Kazutoshi, Kitera, Kazuki, Hirai, Mitsuharu, Kimura, Shinya, Aragane, Naoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294373/
https://www.ncbi.nlm.nih.gov/pubmed/30550608
http://dx.doi.org/10.1371/journal.pone.0209384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294373/
https://www.ncbi.nlm.nih.gov/pubmed/30550608
http://dx.doi.org/10.1371/journal.pone.0209384

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