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Mechanisms of acquired resistance to afatinib clarified with liquid biopsy
Although mechanisms of acquired resistance to 1(st) and 3(rd) generation EGFR-TKI continue to be elucidated, there have been few clinical investigations into the mechanisms of acquired resistance to the 2(nd) generation EGFR-TKI afatinib. We analyzed data from 20 patients with advanced lung adenocar...
Autores principales: | Nakamura, Tomomi, Nakashima, Chiho, Komiya, Kazutoshi, Kitera, Kazuki, Hirai, Mitsuharu, Kimura, Shinya, Aragane, Naoko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294373/ https://www.ncbi.nlm.nih.gov/pubmed/30550608 http://dx.doi.org/10.1371/journal.pone.0209384 |
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