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Genome-wide mapping reveals conserved and diverged R-loop activities in the unusual genetic landscape of the African trypanosome genome

R-loops are stable RNA–DNA hybrids that have been implicated in transcription initiation and termination, as well as in telomere maintenance, chromatin formation, and genome replication and instability. RNA Polymerase (Pol) II transcription in the protozoan parasite Trypanosoma brucei is highly unus...

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Detalles Bibliográficos
Autores principales:	Briggs, Emma, Hamilton, Graham, Crouch, Kathryn, Lapsley, Craig, McCulloch, Richard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294496/ https://www.ncbi.nlm.nih.gov/pubmed/30304482 http://dx.doi.org/10.1093/nar/gky928

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