Integration of genetics and miRNA–target gene network identified disease biology implicated in tissue specificity

MicroRNAs (miRNAs) modulate the post-transcriptional regulation of target genes and are related to biology of complex human traits, but genetic landscape of miRNAs remains largely unknown. Given the strikingly tissue-specific miRNA expression profiles, we here expand a previous method to quantitativ...

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Detalles Bibliográficos
Autores principales: Sakaue, Saori, Hirata, Jun, Maeda, Yuichi, Kawakami, Eiryo, Nii, Takuro, Kishikawa, Toshihiro, Ishigaki, Kazuyoshi, Terao, Chikashi, Suzuki, Ken, Akiyama, Masato, Suita, Naomasa, Masuda, Tatsuo, Ogawa, Kotaro, Yamamoto, Kenichi, Saeki, Yukihiko, Matsushita, Masato, Yoshimura, Maiko, Matsuoka, Hidetoshi, Ikari, Katsunori, Taniguchi, Atsuo, Yamanaka, Hisashi, Kawaji, Hideya, Lassmann, Timo, Itoh, Masayoshi, Yoshitomi, Hiroyuki, Ito, Hiromu, Ohmura, Koichiro, R Forrest, Alistair R, Hayashizaki, Yoshihide, Carninci, Piero, Kumanogoh, Atsushi, Kamatani, Yoichiro, de Hoon, Michiel, Yamamoto, Kazuhiko, Okada, Yukinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294505/
https://www.ncbi.nlm.nih.gov/pubmed/30407537
http://dx.doi.org/10.1093/nar/gky1066

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