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Structural basis of the specific interaction of SMRT corepressor with histone deacetylase 4

Modification of chromatin and related transcription factors by histone deacetylases (HDACs) is one of the major strategies for controlling gene expression in eukaryotes. The HDAC domains of class IIa HDACs repress the respective target genes by interacting with the C-terminal region of the silencing...

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Detalles Bibliográficos
Autores principales: Park, Suk-Youl, Kim, Gwang Sik, Hwang, Hyo-Jeong, Nam, Taek-Hyun, Park, Hee-Sae, Song, Jaeyoung, Jang, Tae-Ho, Lee, Young Chul, Kim, Jeong-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294515/
https://www.ncbi.nlm.nih.gov/pubmed/30321390
http://dx.doi.org/10.1093/nar/gky926