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Structure of human telomere G-quadruplex in the presence of a model drug along the thermal unfolding pathway

A multi-technique approach, combining circular dichroism spectroscopy, ultraviolet resonance Raman spectroscopy and small angle scattering techniques, has been deployed to elucidate how the structural features of the human telomeric G-quadruplex d[A(GGGTTA)3GGG] (Tel22) change upon thermal unfolding...

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Detalles Bibliográficos
Autores principales:	Bianchi, Federico, Comez, Lucia, Biehl, Ralf, D’Amico, Francesco, Gessini, Alessandro, Longo, Marialucia, Masciovecchio, Claudio, Petrillo, Caterina, Radulescu, Aurel, Rossi, Barbara, Sacchetti, Francesco, Sebastiani, Federico, Violini, Nicolò, Paciaroni, Alessandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294516/ https://www.ncbi.nlm.nih.gov/pubmed/30407585 http://dx.doi.org/10.1093/nar/gky1092

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