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Structural insights into the duplex DNA processing of TREX2

The three prime repair exonuclease 2 (TREX2) is an essential 3′-to-5′ exonuclease that functions in cell proliferation, genome integrity and skin homeostasis maintenance. The abnormal expression level of TREX2 can result in broken chromosome, increased susceptibility to skin carcinogenesis and Psori...

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Detalles Bibliográficos
Autores principales:	Cheng, Hiu-Lo, Lin, Chun-Ting, Huang, Kuan-Wei, Wang, Shuying, Lin, Yeh-Tung, Toh, Shu-Ing, Hsiao, Yu-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294518/ https://www.ncbi.nlm.nih.gov/pubmed/30357414 http://dx.doi.org/10.1093/nar/gky970

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