IRES-dependent ribosome repositioning directs translation of a +1 overlapping ORF that enhances viral infection

RNA structures can interact with the ribosome to alter translational reading frame maintenance and promote recoding that result in alternative protein products. Here, we show that the internal ribosome entry site (IRES) from the dicistrovirus Cricket paralysis virus drives translation of the 0-frame...

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Detalles Bibliográficos
Autores principales: Kerr, Craig H, Wang, Qing S, Moon, Kyung-Mee, Keatings, Kathleen, Allan, Douglas W, Foster, Leonard J, Jan, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294563/
https://www.ncbi.nlm.nih.gov/pubmed/30418631
http://dx.doi.org/10.1093/nar/gky1121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294563/
https://www.ncbi.nlm.nih.gov/pubmed/30418631
http://dx.doi.org/10.1093/nar/gky1121

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