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IRES-dependent ribosome repositioning directs translation of a +1 overlapping ORF that enhances viral infection
RNA structures can interact with the ribosome to alter translational reading frame maintenance and promote recoding that result in alternative protein products. Here, we show that the internal ribosome entry site (IRES) from the dicistrovirus Cricket paralysis virus drives translation of the 0-frame...
Autores principales: | Kerr, Craig H, Wang, Qing S, Moon, Kyung-Mee, Keatings, Kathleen, Allan, Douglas W, Foster, Leonard J, Jan, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294563/ https://www.ncbi.nlm.nih.gov/pubmed/30418631 http://dx.doi.org/10.1093/nar/gky1121 |
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