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Epitomic Characterization of the Specificity of the Anti-Amyloid Aβ Monoclonal Antibodies 6E10 and 4G8

The monoclonal antibodies 6E10 and 4G8 are among the first anti-amyloid monoclonal antibodies against Aβ and the most widely used antibodies in Alzheimer’s disease research. Although the epitopes for 6E10 and 4G8 have been reported to correspond to residues 1–16 and 17–24, a more recent high-resolut...

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Detalles Bibliográficos
Autores principales: Baghallab, Ibtisam, Reyes-Ruiz, Jorge Mauricio, Abulnaja, Khalid, Huwait, Etimad, Glabe, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294585/
https://www.ncbi.nlm.nih.gov/pubmed/30412489
http://dx.doi.org/10.3233/JAD-180582