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LOTUS Inhibits Neuronal Apoptosis and Promotes Tract Regeneration in Contusive Spinal Cord Injury Model Mice
Nogo receptor-1 (NgR1) signaling is involved in the limitation of axonal regeneration following spinal cord injury (SCI) through collapsing the growth cone and inhibiting neurite outgrowth. Lateral olfactory tract usher substance (LOTUS), a NgR antagonist, suppresses these pathological conditions. A...
Autores principales: | Ito, Shuhei, Nagoshi, Narihito, Tsuji, Osahiko, Shibata, Shinsuke, Shinozaki, Munehisa, Kawabata, Soya, Kojima, Kota, Yasutake, Kaori, Hirokawa, Tomoko, Matsumoto, Morio, Takei, Kohtaro, Nakamura, Masaya, Okano, Hideyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294604/ https://www.ncbi.nlm.nih.gov/pubmed/30560203 http://dx.doi.org/10.1523/ENEURO.0303-18.2018 |
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