Elevated Notch1 enhances interleukin-22 production by CD4(+) T cells via aryl hydrocarbon receptor in patients with lung adenocarcinoma

Notch signaling induced interleukin (IL)-22 secretion by CD4(+) T cells via retinoid-related orphan nuclear receptor γt (RORγt) or aryl hydrocarbon receptor (AhR). Previous studies have demonstrated that Notch-AhR-IL-22 axis took part in the pathogenesis of chronic viral infection, however, its role...

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Detalles Bibliográficos
Autores principales: Pang, Bo, Hu, Cong, Xing, Na, Xu, Lei, Zhang, Songling, Yu, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294615/
https://www.ncbi.nlm.nih.gov/pubmed/30473538
http://dx.doi.org/10.1042/BSR20181922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294615/
https://www.ncbi.nlm.nih.gov/pubmed/30473538
http://dx.doi.org/10.1042/BSR20181922

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