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Down-regulation of ABCE1 inhibits temozolomide resistance in glioma through the PI3K/Akt/NF-κB signaling pathway

The ATP binding cassette (ABC) E1 (ABCE1), a member of the ABC family, was originally described as the RNase L inhibitor. Through forming a heterodimer with RNase L, ABCE1 participates in the negative regulation of the 2-5A/RNase L system and thus mediates a wide range of biological functions. Recen...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Chen, Xiao-Bing, Ding, Bing-Qian, Liu, Hong-Lin, He, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294624/
https://www.ncbi.nlm.nih.gov/pubmed/30455394
http://dx.doi.org/10.1042/BSR20181711