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Resetting the ligand binding site of placental protein 13/galectin-13 recovers its ability to bind lactose

Placental protein 13/galectin-13 (Gal-13) is highly expressed in placenta, where its lower expression is related to pre-eclampsia. Recently, the crystal structures of wild-type Gal-13 and its variant R53H at high resolution were solved. The crystallographic and biochemical results showed that Gal-13...

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Detalles Bibliográficos
Autores principales:	Su, Jiyong, Cui, Linlin, Si, Yunlong, Song, Chenyang, Li, Yuying, Yang, Tong, Wang, Hao, Mayo, Kevin H., Tai, Guihua, Zhou, Yifa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294630/ https://www.ncbi.nlm.nih.gov/pubmed/30413611 http://dx.doi.org/10.1042/BSR20181787

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