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Osteogenic protein-1 attenuates nucleus pulposus cell apoptosis through activating the PI3K/Akt/mTOR pathway in a hyperosmotic culture

Background: Previous studies have indicated that osteogenic protein-1 has protective effects on the biological functions of intervertebral disc cells. Hyperosmolarity is an important physicochemical factor within the disc nucleus pulposus (NP) region, which obviously promotes NP cell apoptosis. Obje...

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Detalles Bibliográficos
Autores principales:	Yang, Yan, Wang, Xiyang, Liu, Zheng, Xiao, Xiao, Hu, Wenkai, Sun, Zhicheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294645/ https://www.ncbi.nlm.nih.gov/pubmed/30459239 http://dx.doi.org/10.1042/BSR20181708

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