Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 glycoprotein

Eastern equine encephalitis virus (EEEV) is a mosquito-transmitted alphavirus with a high case mortality rate in humans. EEEV is a biodefense concern because of its potential for aerosol spread and the lack of existing countermeasures. In this study, we identified a panel of 18 neutralizing murine m...

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Detalles Bibliográficos
Autores principales: Kim, Arthur S., Austin, S. Kyle, Gardner, Christina L., Zuiani, Adam, Reed, Douglas S., Trobaugh, Derek W., Sun, Chengqun, Basore, Katherine, Williamson, Lauren E., Crowe, James E., Slifka, Mark K., Fremont, Daved H., Klimstra, William B., Diamond, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294662/
https://www.ncbi.nlm.nih.gov/pubmed/30455470
http://dx.doi.org/10.1038/s41564-018-0286-4

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