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Legionella pneumophila inhibits immune signaling via MavC-mediated transglutaminase-induced ubiquitination of UBE2N
The bacterial pathogen Legionella pneumophila modulates host immunity using effectors translocated by its Dot/Icm transporter to facilitate its intracellular replication. A number of these effectors employ diverse mechanisms to interfere with protein ubiquitination, a posttranslational modification...
Autores principales: | Gan, Ninghai, Nakayasu, Ernesto S., Hollenbeck, Peter J., Luo, Zhao-Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294664/ https://www.ncbi.nlm.nih.gov/pubmed/30420781 http://dx.doi.org/10.1038/s41564-018-0282-8 |
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