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Epstein-Barr virus BORF2 inhibits cellular APOBEC3B to preserve viral genome integrity

The APOBEC family of single-stranded (ss)DNA cytosine deaminases provides innate immunity against virus and transposon replication(1–4). A well-studied mechanism is APOBEC3G restriction of HIV-1, which is counteracted by a virus-encoded degradation mechanism(1–4). Accordingly, most work has focused...

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Detalles Bibliográficos
Autores principales: Cheng, Adam Z., Yockteng-Melgar, Jaime, Jarvis, Matthew C., Malik-Soni, Natasha, Borozan, Ivan, Carpenter, Michael A., McCann, Jennifer L., Ebrahimi, Diako, Shaban, Nadine M., Marcon, Edyta, Greenblatt, Jack, Brown, William L., Frappier, Lori, Harris, Reuben S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294688/
https://www.ncbi.nlm.nih.gov/pubmed/30420783
http://dx.doi.org/10.1038/s41564-018-0284-6