Cargando…

Epstein-Barr virus BORF2 inhibits cellular APOBEC3B to preserve viral genome integrity

The APOBEC family of single-stranded (ss)DNA cytosine deaminases provides innate immunity against virus and transposon replication(1–4). A well-studied mechanism is APOBEC3G restriction of HIV-1, which is counteracted by a virus-encoded degradation mechanism(1–4). Accordingly, most work has focused...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheng, Adam Z., Yockteng-Melgar, Jaime, Jarvis, Matthew C., Malik-Soni, Natasha, Borozan, Ivan, Carpenter, Michael A., McCann, Jennifer L., Ebrahimi, Diako, Shaban, Nadine M., Marcon, Edyta, Greenblatt, Jack, Brown, William L., Frappier, Lori, Harris, Reuben S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294688/ https://www.ncbi.nlm.nih.gov/pubmed/30420783 http://dx.doi.org/10.1038/s41564-018-0284-6

Ejemplares similares

Cryo-EM structure of the EBV ribonucleotide reductase BORF2 and mechanism of APOBEC3B inhibition
por: Shaban, Nadine M., et al.
Publicado: (2022)

Epstein-Barr Virus BGLF2 commandeers RISC to interfere with cellular miRNA function
por: Campbell, Ashley M., et al.
Publicado: (2022)

Regulation of Epstein-Barr Virus Minor Capsid Protein BORF1 by TRIM5α
por: Lin, Lih-Tsern, et al.
Publicado: (2022)

Mutation Signatures Including APOBEC in Cancer Cell Lines
por: Jarvis, Matthew C, et al.
Publicado: (2018)

The Epstein-Barr Virus EBNA1 Protein
por: Frappier, Lori
Publicado: (2012)

Epstein-Barr virus: Current questions and challenges
por: Frappier, Lori
Publicado: (2021)

Changes in SUMO-modified proteins in Epstein-Barr virus infection identifies reciprocal regulation of TRIM24/28/33 complexes and the lytic switch BZLF1
por: De La Cruz-Herrera, Carlos F., et al.
Publicado: (2023)

Contributions of Epstein–Barr Nuclear Antigen 1 (EBNA1) to Cell Immortalization and Survival
por: Frappier, Lori
Publicado: (2012)

APOBEC3G and APOBEC3F rarely co-mutate the same HIV genome
por: Ebrahimi, Diako, et al.
Publicado: (2012)

Identification and Characterization of USP7 Targets in Cancer Cells
por: Georges, Anna, et al.
Publicado: (2018)

Author Correction: Identification and Characterization of USP7 Targets in Cancer Cells
por: Georges, Anna, et al.
Publicado: (2019)

Genetic and mechanistic basis for APOBEC3H alternative splicing, retrovirus restriction, and counteraction by HIV-1 protease
por: Ebrahimi, Diako, et al.
Publicado: (2018)

The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis
por: Starrett, Gabriel J., et al.
Publicado: (2016)

Insights into the Motif Preference of APOBEC3 Enzymes
por: Ebrahimi, Diako, et al.
Publicado: (2014)

Epstein-Barr Nuclear Antigen 1 Contributes to Nasopharyngeal Carcinoma through Disruption of PML Nuclear Bodies
por: Sivachandran, Nirojini, et al.
Publicado: (2008)

Human APOBEC3 Variations and Viral Infection
por: Sadeghpour, Shiva, et al.
Publicado: (2021)

Opossum APOBEC1 is a DNA mutator with retrovirus and retroelement restriction activity
por: Ikeda, Terumasa, et al.
Publicado: (2017)

APOBEC3 has not left an evolutionary footprint on the HIV-1 Genome
por: Ebrahimi, Diako, et al.
Publicado: (2011)

USP7 Regulates Cytokinesis through FBXO38 and KIF20B
por: Georges, Anna, et al.
Publicado: (2019)

A Role for the Nucleosome Assembly Proteins TAF-Iβ and NAP1 in the Activation of BZLF1 Expression and Epstein-Barr Virus Reactivation
por: Mansouri, Sheila, et al.
Publicado: (2013)

Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B
por: Shi, K., et al.
Publicado: (2016)

APOBECs and Herpesviruses
por: Cheng, Adam Z., et al.
Publicado: (2021)

EBNA1-Mediated Recruitment of a Histone H2B Deubiquitylating Complex to the Epstein-Barr Virus Latent Origin of DNA Replication
por: Sarkari, Feroz, et al.
Publicado: (2009)

A genome-wide screen of Epstein-Barr virus proteins that modulate host SUMOylation identifies a SUMO E3 ligase conserved in herpesviruses
por: De La Cruz-Herrera, Carlos F., et al.
Publicado: (2018)

Epstein-Barr virus is not detected in mucosal lichen planus
por: Danielsson, Karin, et al.
Publicado: (2018)

Characterization of the mechanism by which the RB/E2F pathway controls expression of the cancer genomic DNA deaminase APOBEC3B
por: Roelofs, Pieter A, et al.
Publicado: (2020)

HIV-1 Vif Triggers Cell Cycle Arrest by Degrading Cellular PPP2R5 Phospho-regulators
por: Salamango, Daniel J., et al.
Publicado: (2019)

The Epstein-Barr Virus
por: Payne, L. N.
Publicado: (1980)

APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer
por: McCann, Jennifer L., et al.
Publicado: (2023)

HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation
por: Nakano, Yusuke, et al.
Publicado: (2017)

Correction: HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation
por: Nakano, Yusuke, et al.
Publicado: (2017)

Cytotoxic CD4+ T-cells specific for EBV capsid antigen BORF1 are maintained in long-term latently infected healthy donors
por: Dowell, Alexander C., et al.
Publicado: (2021)

Epstein - Barr virus Pneumonitis
por: McManus, Terence E, et al.
Publicado: (2009)

Epstein–Barr virus vaccines
por: Cohen, Jeffrey I
Publicado: (2015)

Epstein–barr virus vaccines
por: Cohen, Jeffrey I
Publicado: (2015)

Epstein-Barr virus and skin
por: Sangueza-Acosta, Martin, et al.
Publicado: (2018)

Epstein-Barr Virus Gastritis
por: Oki, Masayuki, et al.
Publicado: (2017)

Resurrecting Epstein–Barr Virus
por: Paganelli, Roberto
Publicado: (2022)

Epstein–Barr virus and malaria upregulate AID and APOBEC3 enzymes, but only AID seems to play a major mutagenic role in Burkitt lymphoma
por: Summerauer, Andrea M., et al.
Publicado: (2022)

Potential Cellular Functions of Epstein-Barr Nuclear Antigen 1 (EBNA1) of Epstein-Barr Virus
por: Smith, Danielle Westhoff, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_pl8sdhfc912tqp2iioeaunuvou