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Antidepressants act by inducing autophagy controlled by sphingomyelin–ceramide

Major depressive disorder (MDD) is a common and severe disease characterized by mood changes, somatic alterations, and often suicide. MDD is treated with antidepressants, but the molecular mechanism of their action is unknown. We found that widely used antidepressants such as amitriptyline and fluox...

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Detalles Bibliográficos
Autores principales: Gulbins, Anne, Schumacher, Fabian, Becker, Katrin Anne, Wilker, Barbara, Soddemann, Matthias, Boldrin, Francesco, Müller, Christian P., Edwards, Michael J., Goodman, Michael, Caldwell, Charles C., Kleuser, Burkhard, Kornhuber, Johannes, Szabo, Ildiko, Gulbins, Erich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294742/
https://www.ncbi.nlm.nih.gov/pubmed/30038230
http://dx.doi.org/10.1038/s41380-018-0090-9