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Plasmodium falciparum infected erythrocytes can bind to host receptors integrins αVβ3 and αVβ6 through DBLδ1_D4 domain of PFL2665c PfEMP1 protein
Major complications and mortality from Plasmodium falciparum malaria are associated with cytoadhesion of parasite-infected erythrocytes (IE). The main parasite ligands for cytoadhesion are members of the P. falciparum erythrocyte membrane protein 1 (PfEMP1) family. Interactions of different host rec...
Autores principales: | Chesnokov, Olga, Merritt, Jordan, Tcherniuk, Sergey O., Milman, Neta, Oleinikov, Andrew V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294747/ https://www.ncbi.nlm.nih.gov/pubmed/30552383 http://dx.doi.org/10.1038/s41598-018-36071-2 |
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