Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression

Growing evidence suggests that the glutamatergic modulator ketamine has rapid antidepressant effects in treatment-resistant depressed subjects. The anticholinergic agent scopolamine has also shown promise as a rapid-acting antidepressant. This study applied genome-wide markers to investigate the rol...

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Detalles Bibliográficos
Autores principales: Guo, Wei, Machado-Vieira, Rodrigo, Mathew, Sanjay, Murrough, James W., Charney, Dennis S., Grunebaum, Matthew, Oquendo, Maria A., Kadriu, Bashkim, Akula, Nirmala, Henter, Ioline, Yuan, Peixiong, Merikangas, Kathleen, Drevets, Wayne, Furey, Maura, Mann, J. John, McMahon, Francis J., Zarate Jr., Carlos A., Shugart, Yin Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294748/
https://www.ncbi.nlm.nih.gov/pubmed/30552317
http://dx.doi.org/10.1038/s41398-018-0311-7

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