Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration

Cancer immunotherapy has emerged as an effective therapy in a variety of cancers. However, a key challenge in the field is that only a subset of patients who receive immunotherapy exhibit durable response. It has been hypothesized that host genetics influences the inherent immune profiles of patient...

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Detalles Bibliográficos
Autores principales: Lim, Yoong Wearn, Chen-Harris, Haiyin, Mayba, Oleg, Lianoglou, Steve, Wuster, Arthur, Bhangale, Tushar, Khan, Zia, Mariathasan, Sanjeev, Daemen, Anneleen, Reeder, Jens, Haverty, Peter M., Forrest, William F., Brauer, Matthew, Mellman, Ira, Albert, Matthew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294879/
https://www.ncbi.nlm.nih.gov/pubmed/30463956
http://dx.doi.org/10.1073/pnas.1804506115

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