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Cancer-associated fibroblasts suppress SOX2-induced dysplasia in a lung squamous cancer coculture

Tumorigenesis depends on intricate interactions between genetically altered tumor cells and their surrounding microenvironment. While oncogenic drivers in lung squamous carcinoma (LUSC) have been described, the role of stroma in modulating tissue architecture, particularly cell polarity, remains unc...

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Detalles Bibliográficos
Autores principales:	Chen, Shuang, Giannakou, Andreas, Wyman, Sarah, Gruzas, Janet, Golas, Jonathon, Zhong, Wenyan, Loreth, Christine, Sridharan, Latha, Yamin, Ting-Ting, Damelin, Marc, Geles, Kenneth G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2018
Materias:	PNAS Plus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294935/ https://www.ncbi.nlm.nih.gov/pubmed/30487219 http://dx.doi.org/10.1073/pnas.1803718115

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