Properties of LINE-1 proteins and repeat element expression in the context of amyotrophic lateral sclerosis

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease involving loss of motor neurons and having no known cure and uncertain etiology. Several studies have drawn connections between altered retrotransposon expression and ALS. Certain features of the LINE-1 (L1) retrotr...

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Detalles Bibliográficos
Autores principales: Pereira, Gavin C., Sanchez, Laura, Schaughency, Paul M., Rubio-Roldán, Alejandro, Choi, Jungbin A., Planet, Evarist, Batra, Ranjan, Turelli, Priscilla, Trono, Didier, Ostrow, Lyle W., Ravits, John, Kazazian, Haig H., Wheelan, Sarah J., Heras, Sara R., Mayer, Jens, García-Pérez, Jose Luis, Goodier, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295051/
https://www.ncbi.nlm.nih.gov/pubmed/30564290
http://dx.doi.org/10.1186/s13100-018-0138-z

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