Epigenetic reprogramming of epithelial mesenchymal transition in triple negative breast cancer cells with DNA methyltransferase and histone deacetylase inhibitors

BACKGROUND: Triple negative breast cancer (TNBC) is an aggressive neoplasia with no effective therapy. Our laboratory has developed a unique TNBC cell model presenting epithelial mesenchymal transition (EMT) a process known to be important for tumor progression and metastasis. There is increasing ev...

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Detalles Bibliográficos
Autores principales: Su, Yanrong, Hopfinger, Nathan R., Nguyen, Theresa D., Pogash, Thomas J., Santucci-Pereira, Julia, Russo, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295063/
https://www.ncbi.nlm.nih.gov/pubmed/30547810
http://dx.doi.org/10.1186/s13046-018-0988-8

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