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The suppressive effect of co-inhibiting PD-1 and CTLA-4 expression on H22 hepatomas in mice

OBJECTIVE: We investigated the suppressive effect of siRNA-mediated co-inhibition of PD-1 and CTLA-4 expression on H22 hepatomas in mice. METHODS: Murine H22 cells were cultured in vivo in ICR mice. An allograft tumor model was also established in another ICR mouse group. The tumor-bearing mice were...

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Detalles Bibliográficos
Autores principales:	Liang, Leilei, Ge, Keli, Zhang, Fengying, Ge, Yinlin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295075/ https://www.ncbi.nlm.nih.gov/pubmed/30564277 http://dx.doi.org/10.1186/s11658-018-0122-0

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