LncRNA H19 promotes the proliferation of pulmonary artery smooth muscle cells through AT(1)R via sponging let-7b in monocrotaline-induced pulmonary arterial hypertension

BACKGROUND: Pulmonary arterial hypertension (PAH) is related to inflammation, and the lncRNA H19 is associated with inflammation. However, whether PDGF-BB-H19-let-7b-AT(1)R axis contributes to the pathogenesis of PAH has not been thoroughly elucidated to date. This study investigated the role of H19...

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Detalles Bibliográficos
Autores principales: Su, Hua, Xu, Xiaoling, Yan, Chao, Shi, Yangfeng, Hu, Yanjie, Dong, Liangliang, Ying, Songmin, Ying, Kejing, Zhang, Ruifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295077/
https://www.ncbi.nlm.nih.gov/pubmed/30547791
http://dx.doi.org/10.1186/s12931-018-0956-z

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