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Unified Cox model based multifactor dimensionality reduction method for gene-gene interaction analysis of the survival phenotype
BACKGROUND: One strategy for addressing missing heritability in genome-wide association study is gene-gene interaction analysis, which, unlike a single gene approach, involves high-dimensionality. The multifactor dimensionality reduction method (MDR) has been widely applied to reduce multi-levels of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295107/ https://www.ncbi.nlm.nih.gov/pubmed/30564286 http://dx.doi.org/10.1186/s13040-018-0189-1 |