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Unified Cox model based multifactor dimensionality reduction method for gene-gene interaction analysis of the survival phenotype

BACKGROUND: One strategy for addressing missing heritability in genome-wide association study is gene-gene interaction analysis, which, unlike a single gene approach, involves high-dimensionality. The multifactor dimensionality reduction method (MDR) has been widely applied to reduce multi-levels of...

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Detalles Bibliográficos
Autores principales: Lee, Seungyeoun, Son, Donghee, Kim, Yongkang, Yu, Wenbao, Park, Taesung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295107/
https://www.ncbi.nlm.nih.gov/pubmed/30564286
http://dx.doi.org/10.1186/s13040-018-0189-1