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Genetic interactions between specific chromosome copy number alterations dictate complex aneuploidy patterns

Cells that contain an abnormal number of chromosomes are called aneuploid. High rates of aneuploidy in cancer are correlated with an increased frequency of chromosome missegregation, termed chromosomal instability (CIN). Both high levels of aneuploidy and CIN are associated with cancers that are res...

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Detalles Bibliográficos
Autores principales:	Ravichandran, Madhwesh C., Fink, Sarah, Clarke, Matthew N., Hofer, Franziska Christina, Campbell, Christopher S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295164/ https://www.ncbi.nlm.nih.gov/pubmed/30463904 http://dx.doi.org/10.1101/gad.319400.118

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