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Phosphorylation by the stress-activated MAPK Slt2 down-regulates the yeast TOR complex 2

Saccharomyces cerevisiae target of rapamycin (TOR) complex 2 (TORC2) is an essential regulator of plasma membrane lipid and protein homeostasis. How TORC2 activity is modulated in response to changes in the status of the cell envelope is unclear. Here we document that TORC2 subunit Avo2 is a direct...

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Detalles Bibliográficos
Autores principales: Leskoske, Kristin L., Roelants, Françoise M., Emmerstorfer-Augustin, Anita, Augustin, Christoph M., Si, Edward P., Hill, Jennifer M., Thorner, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295167/
https://www.ncbi.nlm.nih.gov/pubmed/30478248
http://dx.doi.org/10.1101/gad.318709.118

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