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RNA m(6) A modification enzymes shape innate responses to DNA by regulating interferon β

Modification of mRNA by N(6)-adenosine methylation (m(6)A) on internal bases influences gene expression in eukaryotes. How the dynamic genome-wide landscape of m(6)A-modified mRNAs impacts virus infection and host immune responses remains poorly understood. Here, we show that type I interferon (IFN)...

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Detalles Bibliográficos
Autores principales: Rubio, Rosa M., Depledge, Daniel P., Bianco, Christopher, Thompson, Letitia, Mohr, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295168/
https://www.ncbi.nlm.nih.gov/pubmed/30463905
http://dx.doi.org/10.1101/gad.319475.118